Barely Significant
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Broad cross-T cell immunity between emerging SARS-CoV-2 serotypes waved by spike-signature mutations.

Emerg Microbes Infect · 2026 · PMC12829424 · PMID 41566607

Europe PMCDOI
2
hedged sentences
0.0001
closest p · 0.0× alpha
0.0001
boldest claim

The sentences

a decreasing trendP < 0.0001actually significant
Pairwise reduction curves showed a decreasing trend on transitioning from Serotype I to II ( P < 0.0001) in 34/48 (70.8%) samples, from Serotype I to III ( P = 0.0281) in 30/48 (62.5%) samples, and from Serotype I to IV ( P < 0.0001) in 38/48 (79.2%) samples ( Figure 5 (C)).

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did not reach statistical significanceno p-value reported
showed a trendno p-value reported
Although the primary infection group did not reach statistical significance due to sample size limitations, the median T cell response also showed a trend of BA.2.86/JN.1 being lower than that of the XBB series subvariants.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.