Single-cell transcriptomics reveals a novel mechanism of RDH16 regulating immune infiltration in hepatocellular carcinoma.

Front Immunol · 2025 · PMC12832884 · PMID 41601632

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.1600

boldest claim

The sentences

near-significantP = 0.053so close (0.05 < p ≤ 0.1)

The Simple mode method showed a near-significant OR of 0.667 (95% CI: 0.471-0.947, P = 0.053), while the MR Egger and Weighted mode methods did not yield statistically significant results.

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did not reach statistical significancep = 0.16not close (p > 0.1)

First, in the HCCDB18 cohort, the association between RDH16 expression and patient survival did not reach statistical significance (p = 0.16).

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