The effect of omega-3 polyunsaturated fatty acids on short-chain fatty acid production and the gut microbiome in an <i>in vitro</i> colonic fermentation model.

Gut Microbiome (Camb) · 2026 · PMC12835959 · PMID 41608298

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near-significantno p-value reported

Although total SCFA levels were not reported, there was a statistically significant increase in plasma isobutyrate and isovalerate levels (and a near-significant increase in plasma butyrate levels) following the omega-3 PUFA intervention, which mirrored findings in the inulin intervention group (Vijay et al., 2021 ).

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did not reach statistical significanceno p-value reported

The increase in acetate and propionate levels in inulin-containing fermentations in the presence of omega-3 PUFAs did not reach statistical significance ( Table 4 ).

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