Barely Significant
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Thiol/Disulfide Homeostasis in Lung Cancer: Insights from a Clinical Study.

Antioxidants (Basel) · 2026 · PMC12837431 · PMID 41596172

2
hedged sentences
0.0530
closest p · 1.1× alpha
0.0530
boldest claim

The sentences

failed to reach statistical significancep = 0.053so close (0.05 < p ≤ 0.1)
A modest elevation in the disulfide/NT and disulfide/TT ratios was observed in squamous cell carcinoma cases (median: 7.5% and 6.5%, respectively) compared with adenocarcinoma and small cell carcinoma; however, this variation failed to reach statistical significance ( p = 0.053).

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Although oxidative markers tended to worsen with advancing cancer stage, these differences did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.