Proteome-Wide Serological Profiling Reveals Broad Elevation of EBV Immunity in Idiopathic Pulmonary Fibrosis.

Int J Mol Sci · 2026 · PMC12841087 · PMID 41596435

Europe PMC DOI

hedged sentences

0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

did not reach statistical significancep = 0.10so close (0.05 < p ≤ 0.1)

Neither sex ( p = 0.53) nor age ( p = 0.45) was independently associated with global EBV IgG, and the disease-by-sex interaction term did not reach statistical significance ( p = 0.10), indicating no strong evidence that the IPF effect differed by sex.

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nominally significantno p-value reported

Although no single antigen met a stringent FDR significance threshold, 10 EBV antigen-specific antibody responses showed nominal elevation in IPF, with 2 remaining nominally significant after sex adjustment and 5 additional antibody responses reaching significance only in linear regression models.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.