Barely Significant
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Comparative effects of MKARE® eggshell membrane and hydrolyzed collagen as nutricosmetics on skin biophysical properties: a randomized clinical trial.

Front Nutr · 2025 · PMC12846929 · PMID 41613921

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a clear trendno p-value reported
In the pilot phase, MKARE® intake led to a nearly 20% increase in firmness and an approximately 40% rise in hydration, outperforming placebo in firmness and showing a clear trend toward superior hydration despite variability in the control group.

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While some of these results did not reach statistical significance, the consistent trend toward improvement observed in the MKARE® group suggests a positive effect on skin structure.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.