Comprehensive evaluation of GLP-1 receptor agonists: an umbrella review of clinical outcomes across multiple diseases.

Nat Commun · 2026 · PMC12847739 · PMID 41501059

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showed a trendno p-value reported

MI: GLP-1 RAs showed a trend toward a reduced risk of myocardial infarction (MI), including acute subtypes.

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did not reach statistical significanceno p-value reported

Some outcomes did not reach statistical significance in all populations, highlighting the need for further high-quality clinical research.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.