mGluR4-NPDC1 complex mediates α-synuclein fibril-induced neurodegeneration.

Nat Commun · 2025 · PMC12848103 · PMID 41444258

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showed a trendno p-value reported

In this cohort, A53T mice showed a trend to decrease in body weight, not significantly different from wt littermate controls (Supplementary Fig. 13l ).

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did not reach statistical significanceno p-value reported

While symptomatic benefit did not reach statistical significance, the compounds were safe in PD subjects.

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