ARTEMIS: a pilot study comparing AI-based and expert therapeutic decisions in simulated clinical cases of neuroendocrine neoplasms.

NPJ Digit Med · 2025 · PMC12852134 · PMID 41436590

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0680

boldest claim

The sentences

highly significantp < 0.001actually significant

The difference in concordance between AI systems and experts was highly significant (ΔAC1 + 0.84, 95% CI 0.70–0.90; p < 0.001).

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showed a trendp = 0.068so close (0.05 < p ≤ 0.1)

approached significancep = 0.103not close (p > 0.1)

4 ), higher perceived uncertainty remained a significant predictor of disagreement for baseline GPT (OR 13.99; p = 0.032), while grade showed a trend towards increased discordance (OR 7.32; p = 0.068) and lung primary site approached significance (OR 8.26; p = 0.103).

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