showed a trendp=0.09
No single mutation was significantly associated with recurrence or ctDNA positivity (all p>0.05), though YAP1 showed a trend for recurrence risk (OR=10.7, p=0.09) and CDKN1A for lower ctDNA positivity (OR=0, p=0.07).
No single mutation was significantly associated with recurrence or ctDNA positivity (all p>0.05), though YAP1 showed a trend for recurrence risk (OR=10.7, p=0.09) and CDKN1A for lower ctDNA positivity (OR=0, p=0.07).
KLF5 is a transcription factor known to regulate cell proliferation, differentiation, and angiogenesis in various cancers, including bladder cancer.Specifically, the isoform ENST00000539231 exhibited a highly significant increase in isoform usage in NMIBC compared to normal tissue.While gene expression levels of KLF5 were not significantly different between normal and NMIBC conditions, the substantial alteration in isoform usage of ENST00000539231 suggests a critical role for this specific isoform in NMIBC pathogenesis.
The overall incidence of lymphoceles and symptomatic lymphoceles appeared to be higher in the harmonic group but did not reach statistical significance.