Barely Significant
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Efficacy of non-invasive neuromodulation technologies in improving cognitive function and activities of daily living in patients with Alzheimer's disease, Parkinson's disease, and stroke: a systematic review and network meta-analysis.

J Neuroeng Rehabil · 2026 · PMC12853689 · PMID 41549257

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Although the differences between subgroups did not reach statistical significance, this trend suggests that age may influence the efficacy of the intervention to some extent.

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However, subgroup difference tests failed to reach statistical significance, indicating that while age may influence effect magnitude, it was not a decisive moderating factor in this study.

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a numerical trendno p-value reported
Subgroup analysis stratified by age revealed a numerical trend suggesting younger patients (< 60 years) experienced greater cognitive benefits, while those > 70 years showed relatively weaker improvements.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.