A swine model of severe chronic thromboembolic pulmonary hypertension induced by repeated pulmonary artery long suture injection.

As for the LV, although systolic performance was unaltered there was a clear trend for unloading and impaired relaxation and filling, most likely due to ventricular interdependence.

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CTEPH also showed a trend towards decreased weight gain on follow-up ( Table 2 ). 3.2 Severe CTEPH is accompanied by RV dysfunction On echocardiography, CTEPH presented lower TAPSE, increased RVWT as well as both short PA acceleration times and lengthened ejection times with late systolic notching in PA flow on pulsed-wave Doppler.

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