Barely Significant
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Differential complement pathways and components in the clinical spectrum of systemic lupus erythematosus.

Arthritis Res Ther · 2025 · PMC12859933 · PMID 41454321

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Although ESR levels were higher in the active SLE (median 39.0 mm/H) than in the LDA subgroup (median 16.0 mm/H), this difference did not reach statistical significance after adjustment ( p .adj > 0.05).

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borderline significantno p-value reported
Notably, our findings further revealed that elevated FD and C2 were independently associated with lower eGFR in SLE patients, whereas reduced C1q showed a borderline significant association.

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showed a trendno p-value reported
Plasma C1q (ρ = -0.71, p .adj < 0.001) was significantly inversely correlated with cSLEDAI, while C4 (ρ = -0.42, p .adj = 0.0515) showed a trend toward negative association.

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