Molecular and immune determinants of response in locally advanced deficient DNA mismatch repair/microsatellite instability-high gastric or gastroesophageal junction adenocarcinoma treated with neoadjuvant chemoimmunotherapy.

Additionally, alterations in the Fanconi anemia (FA) pathway were more frequent in responders, though the difference did not reach statistical significance ( P = 0.080) (Fig. 2 C).

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While both response groups showed a trend toward a higher proportion of CD8 + and CD4 + T cells in post-NCIT samples, these differences did not reach statistical significance (Figure S5).

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