Clinical impact of computed tomography-measured skeletal muscle status at the third cervical vertebra on definitive radiotherapy outcomes for head and neck squamous cell carcinoma.

For PFS, multivariate analysis identified PS, clinical stage, and chemotherapy administration as independent prognostic factors, while SMA did not reach statistical significance (HR = 1.070, 95% CI 0.736–1.556, p = 0.722) [Table 3 ].

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Although our study did not reach statistical significance regarding PFS, patients in the low SMA group showed a trend toward poorer outcomes, likely attributable to insufficient statistical power.

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