Although the association between mucositis severity and cGvHD risk did not reach statistical significance in our patients, there was a clear trend, consistent with the finding of moderate-to-severe oral mucositis as an independent risk factor for cGvHD in a recent study with a larger sample size (230 patients). 20 Whether plaque S. sanguinis is citrullinated in these patients and can be found in the circulation or cGvHD target organs is worthy of further research.
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Dental plaque microbiota following allogeneic hematopoietic cell transplantation and risk of chronic graft-<i>versus</i>-host disease.
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