Resuscitation with Blood Products Attenuates Endothelial Glycocalyx Shedding but not the Acute Inflammatory Response to Injury in a Military-relevant Preclinical Porcine Model of Traumatic Hemorrhagic Shock.

Shock · 2026 · PMC12863592 · PMID 41185419

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

failed to reach statistical significanceP = 0.054so close (0.05 < p ≤ 0.1)

For example, there were some markers that showed clear trends towards a treatment effect but failed to reach statistical significance (e.g., HMGB-1; treatment effect: P = 0.054).

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did not reach statistical significanceno p-value reported

While we observed increases in MPO + cells in the liver, lungs, and kidneys in a proportion of the animals in the saline-treated group (consistent with reports by others ( 29 , 45 , 46 )), this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.