Comparative evaluation of the therapeutic efficacy between human amniotic epithelial cells and human umbilical cord mesenchymal stem cells in premature ovarian insufficiency.

Analysis of vascular and inflammatory maker expression showed a moderate decreased in CD34 expression in the Cy group, while the levels of the pro-inflammatory cytokine TNF-α and anti-inflammatory IL-10 were increased, though these changes did not reach statistical significance.

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hAEC-CM produced significantly more nodes than hUC-MSC-CM and showed a trend toward increased branching, though this did not reach statistical significance ( P < 0.05, Fig. 7 F–H).

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