Association between the no-reflow phenomenon and clinical outcomes after endovascular treatment for acute ischemic stroke: A systematic review and meta-analysis.

Eur Stroke J · 2026 · PMC12866224 · PMID 41614468

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did not reach statistical significanceno p-value reported

Although several comparisons did not reach statistical significance, comparable direction of the association between poorer neurological and functional outcomes emerged in the no-reflow phenomenon group.

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borderline non-significantno p-value reported

Three studies 1 , 22 , 24 reported sICH, with a borderline non-significant higher risk among patients with no-reflow (RR 1.88, 95% CI 1.00–3.56; I 2 = 0.0%; Figure 5(b) ).

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