Intranasal vasopressin, but not oxytocin, decreases ethanol intake in socially housed mice.

2 A), when analyzed across three hours post-injection, the effect of Oxt did not reach statistical significance in males and females (Fig. 2 B, treatment: F 1,44 =0.59, p = 0.45, sex: F 1,44 =2.04, p = 0.037, interaction: F 1,44 =0.54, p = 0.28).

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Since our previous experiment with unsweetened 6% EtOH showed a trend towards lower intake in mice co-administered Oxt and L-368,899, we then IN injected these mice with Oxt (3 mg/kg) in the presence of Oxtr antagonist L-368,899 (10 mg/kg, IN).

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