Low HDL cholesterol is associated with elevated TNFR1 and TNFR2 levels in early diabetic kidney disease.

Front Endocrinol (Lausanne) · 2026 · PMC12875942 · PMID 41658514

Europe PMC DOI

hedged sentence

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

did not reach statistical significancep = 0.052so close (0.05 < p ≤ 0.1)

showed a trendp = 0.052so close (0.05 < p ≤ 0.1)

For TNFR2, age and HDL remained significantly associated, whereas UACR showed a trend toward association that did not reach statistical significance ( p = 0.052).

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