Barely Significant
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Progression from acute to chronic pancreatitis in children: a systematic review and meta-analysis.

Clin Exp Pediatr · 2026 · PMC12877302 · PMID 41381081

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a nonsignificant trendno p-value reported
Diabetes mellitus was not associated with RAP, but showed a nonsignificant trend toward an increased risk of CP (OR, 3.77; 95% CI, 0.98–14.45; 95% PI, 0.12–120.85; I 2=0%, τ2=0; k=4 studies, N=169 patients) ( Figs. 3 and 4 ; Supplementary Figs. 2 , 4 , and 6 ).

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showed a trendno p-value reported
Disease severity showed a trend toward higher recurrence rates, although subgroup differences were not statistically significant (χ2=2.60, degrees of freedom [df]=2, P =0.272).

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Interestingly, mutations in SPINK1, CFTR, and CTRC, which have been previously implicated in pancreatitis susceptibility, did not reach statistical significance in our analysis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.