Intestinal microenvironment dynamics and Sepsis-associated encephalopathy pathophysiology: insights from multi-omics profiling.

Although inflammatory markers such as tumor necrosis factor-alpha (TNF- α ), interleukin-6 (IL-6), and C-reactive protein (CRP) showed a trend toward elevation in SAE patients, these differences did not reach statistical significance ( p > 0.05, Supplementary Table S2 ).

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