Barely Significant
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MRI-based clinical-radiomics-habitat model for predicting prognosis of hepatocellular carcinoma patients treated with HAIC.

Front Oncol · 2026 · PMC12890658 · PMID 41684595

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did not reach statistical significancep = 0.28not close (p > 0.1)
Although the difference between the CR and CRH models did not reach statistical significance (Z = –1.071, p = 0.28), bootstrap validation indicated stable model performance (SD of AUC: CR = 0.048, CRH = 0.046).

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showed a trendno p-value reported
Although no statistically significant performance differences were observed between the CRH and CR models, the CRH model exhibited a numerically higher AUC and showed a trend toward distinguishing patients with differing actual early response outcomes, which hints at its potential clinical utility.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.