Barely Significant
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Combined Flexion, Torsion and Compression Drive Distinct Intervertebral Disc Failure Mechanisms Under Asymmetric, High-Cycle Loading.

JOR Spine · 2026 · PMC12892121 · PMID 41684428

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showed a trendno p-value reported
Although the group loaded asymmetrically and with higher cycles showed a trend toward reduced viability in the inner AF and transitional NP relative to the groups loaded symmetrically and with lower cycles, these differences did not reach statistical significance due to an outlier specimen with a high cell viability in the asymmetric group. 3.3.

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