Consistently, the recessive model approached but did not reach significance (OR = 1.606, p = 0.051).
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PD-L1/<i>CD274</i> and miR-155<i>/MIR155HG</i> Genetic Variants as Prognostic and Risk Biomarkers in Diffuse Large B-Cell Lymphoma.
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0.0510
0.0830
The sentences
borderline significantp = 0.051
When stratified by cell-of-origin, the association between rs822336 and RFS was borderline significant in ABC-DLBCL (Kaplan–Meier, p = 0.051), whereas no association was observed in the GCB subtype ( p = 0.300).
a strong trendp = 0.055
Regarding RFS, IPI score emerged as a significant predictor of shorter RFS (HR = 1.633, p = 0.012), while response to therapy showed a strong trend toward association with RFS ( p = 0.055).
Age-stratified analysis further demonstrated that the rs4143815 variant was significantly associated with OS in patients older than 60 years ( p = 0.043), while the trend did not reach statistical significance among patients ≤60 years ( p = 0.083).