SARS-CoV-2 Spike Protein Induces Time-Dependent and Brain-Region-Specific Alterations in Ferroptosis Markers: A Preliminary Study in K18-hACE2 Mice.

Int J Mol Sci · 2026 · PMC12897609 · PMID 41683943

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closest p

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showed a trendno p-value reported

FPN1 showed a significant increase at 2 weeks in the spike group, while TFR1 showed a trend toward higher expression in the spike group at 6 weeks.

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did not reach statistical significanceno p-value reported

However, post hoc Šídák-adjusted comparisons between saline and spike groups at 2, 6, and 12 weeks did not reach statistical significance.

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