Expression Patterns of LALBA and Nucleolin and Their Clinical, Prognostic, and Immune Relevance in Breast Cancer Tissues of Mexican Patients.

Although patients with moderate/high LALBA expression appeared to have shorter median survival than those with low expression ( Figure 3 A), this effect did not reach statistical significance (Kaplan–Meier survival curves, p > 0.05).

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LALBA, a major milk protein normally expressed only during late pregnancy and lactation, was detected in nearly all tumor samples and showed higher levels in aggressive subtypes, with overexpression displaying a slight trend toward poorer overall survival.

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We found that patients with LALBA overexpression showed a trend toward shorter overall survival; however, this finding emerged from an unadjusted, exploratory analysis and is likely influenced by the underlying molecular subtype distribution rather than reflecting an independent prognostic effect of LALBA expression.

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