Sleep Deficit and Inflammatory Markers as Combined Risk Factors for Glaucoma Progression: A Prospective Longitudinal Observational Cohort Study.

Int J Mol Sci · 2026 · PMC12898611 · PMID 41683759

Europe PMC DOI

hedged sentences

0.1990

closest p · 4.0× alpha

0.1990

boldest claim

The sentences

did not reach statistical significancep = 0.199not close (p > 0.1)

IL-6 and TNF-α showed numerical trends toward elevation over time in untreated glaucoma compared to controls, though these group differences in trajectory did not reach statistical significance (IL-6: p = 0.199; TNF-α: p = 0.727).

also in 111,027 other papers

showed a trendno p-value reported

Sleep deficit showed a trend toward worsening inflammation in glaucoma patients, though this did not reach statistical significance in the full cohort (IL-6: p = 0.397; TNF-α: p = 0.174).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.