Barely Significant
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Brain Metastasis After Curative Resection of Non-small Cell Lung Cancer: A Systematic Review and Meta-Analysis.

Cureus · 2026 · PMC12900982 · PMID 41694838

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showed a trendno p-value reported
Pathological N stage showed a trend toward increased risk, but the pooled estimate was not statistically significant and exhibited substantial heterogeneity (HR = 1.66, 95% CI 0.92-3.02, I2 = 67.5%).

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Within this group, micropapillary histology showed a tendency towards increased risk but did not reach statistical significance (HR = 1.27, 95% CI 0.91-1.77, I2 = 51.1%).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.