Myocardial fibrosis predicts sudden cardiac death in patients with hypertrophic cardiomyopathy after cardiac electronic device implantation: Insights from cardiovascular magnetic resonance imaging.

Similarly, compared with 2024 AHA risk factors (AUC 0.76; 95% CI 0.62–0.90; P < .001), adding transmural fibrosis and increased GZF 6SD showed a trend toward improved discrimination (AUC 0.81; 95% CI 0.69–0.94; P < .001; P for AUC comparison = .1; NRI 0.13; 95% CI −0.16 to 0.42; P = .383; IDI 0.07; 95% CI 0.01–0.13; P = .022) ( Supplemental Tables 8 and 9 ; Figure 5 ).

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The other location or pattern of MF did not reach statistical significance in multivariate models ( Figure 2 ; Supplemental Table 3 ).

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