Dydrogesterone and Letrozole Combination for the Treatment of Endometriosis: A Mechanism-Based Therapeutic Approach.

IL‐6 levels also declined, although this decrease did not reach statistical significance relative to the disease control (Figure 6(d) ).

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Leuprolide was associated with a modest trend toward smaller lesions, whereas dienogest showed a trend toward reduced lesion volume, which appeared less pronounced than that observed with the dydrogesterone–letrozole combination.

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