Understanding Risk Factors for Otitis Media in Rural Alaska Native Children: A Cohort Study.

CPT1A arctic variant homozygosity showed a trend toward a positive association with 6-mo cumulative odds of otitis media and moderating the effect of other risk factors on the odds of otitis media incidence.

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Notably, when examined as a modifying effect, CPT1A arctic variant homozygosity appeared to increase the odds of otitis media incidence in those who were never breastfed, though this trend did not reach statistical significance (Fig. 2 ).

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