Comprehensive Analysis of NOTCH1 Mutations in Indian Pediatric ALL Patients: Clinical and Molecular Insights.

Asian Pac J Cancer Prev · 2025 · PMC12905812 · PMID 41148611

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closest p

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marginal significanceno p-value reported

For instance, a p-value of 0.066 was observed for Exon 34 in B-ALL, indicating marginal significance.

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showed a trendno p-value reported

In our study of B-cell acute lymphoblastic leukemia (B-ALL), we observed that cases positive for NOTCH1 mutations in the PEST domain showed a trend towards increased significance in terms of overall survival (OS) compared to cases with mutations in the HD domain when compared with their wildtype counterparts.

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did not reach statistical significanceno p-value reported

It is important to note that while trends were observed in survival outcomes, most p-values did not reach statistical significance, likely due to the sample size, and should be interpreted cautiously.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.