Platelet-to-lymphocyte ratio for prognostication in immune checkpoint inhibitor-treated cancer patients: a meta-analysis of 13027 patients highlighting nivolumab-responsive renal cell carcinoma.

Front Immunol · 2026 · PMC12907331 · PMID 41705252

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did not reach statistical significanceno p-value reported

For OS, elevated PLR did not reach statistical significance in triple-negative breast cancer patients, while all other cancer types demonstrated a significant inverse association between high PLR and OS.

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failed to reach statistical significanceno p-value reported

For PFS, high PLR failed to reach statistical significance in NSCLC (HR = 1.61, 95% CI: 0.99-2.62) but consistently predicted poorer PFS in RCC (HR = 1.79, 95% CI: 1.27-2.51).

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