Proline promotes prolyl 4-hydroxylase subunit alpha 1 via transforming growth factor beta 1 to increase the synthesis and deposition of collagen in grass carp (<i>Ctenopharyngodon idellus</i>) muscle fibroblasts: Insights from integrated bioinformatics and functional analysis.

Furthermore, Pro reversed the down-regulation of col5a1 mRNA relative expression induced by p4ha1 knockdown, although this reversal did not reach statistical significance ( P > 0.05). 3.5.

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3 A) showed a trend of first increasing and then decreasing with the Pro concentration, and it reached the extreme value at 0.9 mmol/L of Pro ( P = 0.390).

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