Multicenter evaluation of prognostic nutritional index and systemic immune-inflammation index in predicting mortality among critically ill cardiovascular and cerebrovascular patients with varied glucose metabolism: a machine learning-based cohort study.

Front Nutr · 2026 · PMC12909231 · PMID 41710272

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a significant trendno p-value reported

In DM patients, the protective effect of T3 was present in Model 1 (HR = 0.591) but was attenuated in Model 3 (HR = 0.957), with a significant trend observed across all populations.

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approached significanceno p-value reported

In Pre-DM patients, only T3 was associated with a significant reduction in risk (Model 1: HR = 0.318; Model 3: HR = 0.472), while T2 approached significance.

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