Barely Significant
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AI-based quantification of tumor-infiltrating lymphocytes with integrative transcriptomics in ovarian clear cell carcinoma: JGOG3025-TR1/A1 study.

Cancer Immunol Immunother · 2026 · PMC12909737 · PMID 41697393

2
hedged sentences
0.0630
closest p · 1.3× alpha
0.3200
boldest claim

The sentences

did not reach statistical significancep = 0.063so close (0.05 < p ≤ 0.1)
The ARID1A mutations were present in 48 cases (25.4%), with slightly higher frequency in the immune group (32.5%) than in the non-immune group (19.8%); however, this difference did not reach statistical significance ( p = 0.063) (Supplementary Fig. 4D).

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showed a trendp = 0.32not close (p > 0.1)
Prognostic analysis revealed that, although not statistically significant, the immune-inflamed group defined by iTIL score showed a trend toward improved PFS (hazard ratio, 0.73; 95% CI, 0.39–1.36; p = 0.32) and OS (hazard ratio, 0.86; 95% CI, 0.41–1.83; p = 0.70) (Fig. 3 C), which was in contrast to the prognostic findings based on transcriptome-based immune classification.

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