Adjunctive probiotic therapy sustains symptom relief in gastroesophageal reflux disease through gut microbiome-metabolome remodeling.

mSystems · 2026 · PMC12911400 · PMID 41609355

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.3650

boldest claim

The sentences

showed a trendP = 0.050actually significant

Notably, putrescine levels were significantly higher in the probiotic group at both weeks 4 and 8 ( P < 0.05), whereas glycine levels showed a trend toward increase at week 12 ( P = 0.050), following the probiotic-only phase.

also in 33,481 other papers

did not reach statistical significanceP = 0.365not close (p > 0.1)

Although the endoscopic healing rate (resolution to LA grade 0) was higher in the probiotic group (36.84%) than in the placebo group (12.50%), the difference did not reach statistical significance ( P = 0.365).

also in 75,868 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.