Comparative Efficacy of Coral Calcium Carried Hydrogen versus Dexamethasone in a Mouse Model of Allergic Contact Dermatitis.

Mechanistically, CCH selectively lowered serum IgE and showed a trend in reducing IL-17, paralleling its specific suppression of lymphocytes.

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While the DNCB group exhibited a three-fold increase in IL-17 levels versus controls, both treatment groups showed reductions (CCH: 42.4%; DEX: 33.4%), though these changes did not reach statistical significance ( Figure 4B ).

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