Functional variants at 1p36.23 confer risk of schizophrenia through modulating RERE.

Nat Commun · 2026 · PMC12914037 · PMID 41580391

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

GluN2B expression also showed a trend toward a decrease; however, this change did not reach statistical significance (Fig. 7a, c ).

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highly significantno p-value reported

The qPCR results of four selected genes ( Erbb4 , Sema5a , Fbln2 , and Mest were selected as they exhibited highly significant P -values, i.e., ranked among the top 20%) and were consistent with RNA-seq (Supplementary Fig. 8 ), indicating the reliability of the transcriptomic analysis.

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