Barely Significant
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Hypofractionated stereotactic radiotherapy versus whole-brain radiotherapy following brain metastasis resection: Results of the ESTRON randomized phase 2 trial.

Neuro Oncol · 2025 · PMC12916734 · PMID 40747537

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did not reach statistical significanceP = .080so close (0.05 < p ≤ 0.1)
showed a trendno p-value reported
Unadjusted Kaplan–Meier curves showed a trend toward prolonged intracranial control in the WBRT arm, although the difference did not reach statistical significance ( Figure 2a , P = .080).

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