Barely Significant
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Anti-inflammatory therapy with low-dose IL-2 in acute coronary syndromes: a randomized phase 2 trial.

Nat Med · 2026 · PMC12920103 · PMID 41507574

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did not reach statistical significanceP = 0.086so close (0.05 < p ≤ 0.1)
showed a trendno p-value reported
In addition, the difference in change from baseline between the groups (Extended Data Table 1a ) showed a trend toward a reduction in arterial inflammation in the low-dose IL-2 group compared to placebo, but did not reach statistical significance (−0.103, 95% CI −0.22 to 0.02, P = 0.086).

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