Right-Sided Extravalvular Damage: An Overlooked Driver of Risk Model Failure in Low-Flow, Low-Gradient Aortic Stenosis.

J Soc Cardiovasc Angiogr Interv · 2026 · PMC12923347 · PMID 41726046

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.2000

boldest claim

The sentences

a suggestive trendP = .06so close (0.05 < p ≤ 0.1)

After incorporating right-sided extravalvular damage into our enhanced model, the AUC increased to 0.67 (95% CI, 0.53-0.80), reflecting a suggestive trend toward improved discrimination ( P = .06).

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did not reach statistical significanceP = .20not close (p > 0.1)

The total NRI was positive (0.10; 95% CI, –0.05 to 0.25) but did not reach statistical significance ( P = .20).

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