Digital Quantification of Progesterone Receptor Expression in Meningiomas: Associations with WHO Grade and Clinicopathological Features.

Among Grade 1 subtypes, fibrous meningiomas showed a trend toward lower PR expression, similar to earlier observations that fibrous morphology may be associated with lower PR levels ( 4 ).

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Within Grade I variants, fibrous and microcystic meningiomas exhibited comparatively lower digital PR H-scores (fibrous: median 114, IQR 105–148; microcystic: median 134, IQR 118–165) relative to other Grade I subtypes, although these differences did not reach statistical significance after multiple-testing correction.

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