Non-cytolytic re-engineering of a viral vaccine vector enables durable effector-memory T cell immunity by reinforcing type I IFN induction.

Mol Ther Nucleic Acids · 2026 · PMC12925560 · PMID 41732204

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highly significantno p-value reported

p < 0.05 (∗) was considered statistically significant and p < 0.01 (∗∗) as highly significant.

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failed to reach statistical significanceno p-value reported

showed a trendno p-value reported

VSVG-pseudotyped vectors showed a trend toward higher CD8 T cell frequencies after booster vaccination, too, but these differences failed to reach statistical significance.

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