Barely Significant
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The predictive value of baseline systemic inflammation response index and systemic immune-inflammation index for the risk of infection within 6 months following initial immunosuppressive treatment in patients with ANCA-associated vasculitis.

Front Immunol · 2026 · PMC12926124 · PMID 41737230

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Although a trend toward a positive association with BVAS was noted (r=0.162, p=0.062), it did not reach statistical significance.

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a positive trendno p-value reported
However, their correlations with the composite clinical activity score BVAS were weaker; SIRI showed a positive trend that did not reach statistical significance, while SII did not show a significant correlation.

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showed a trendno p-value reported
The use of corticosteroids showed a trend toward being more frequent in the infection group (93.5%) compared to the non-infection group (84.2%), with a p-value of 0.055.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.