Comparative Efficacy and Safety of Vasopressors and Inotropes in Acute Myocardial Infarction-Related Cardiogenic Shock: A Systematic Review and Network Meta Analysis of Randomized and Observational Studies.

Cureus · 2026 · PMC12927664 · PMID 41737078

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showed a trendno p-value reported

Norepinephrine showed a trend toward benefit compared with dobutamine (OR = 0.89, 95% CI = 0.70-1.14), although the CI crossed unity.

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did not reach statistical significanceno p-value reported

Norepinephrine was associated with lower mortality than dopamine (OR = 0.85, 95% CI = 0.65-1.12); however, this did not reach statistical significance in the full random-effects model due to the inflated variance from heterogeneity.

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