Association of maternal immunoglobulin G levels with pregnancy outcomes in primary immunodeficiency: A retrospective single-center study.

Medicine (Baltimore) · 2026 · PMC12928920 · PMID 41731816

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.1090

boldest claim

The sentences

borderline significanceP = .053so close (0.05 < p ≤ 0.1)

No significant links were found between third-trimester IgG and neonatal outcomes, except for a borderline significance for NICU admission ( P = .053; Table 6 ). 3.6.

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showed a trendP = .081so close (0.05 < p ≤ 0.1)

Lower IgG levels showed a trend toward higher PID-related maternal infections ( P = .081).

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did not reach statistical significanceP = .109not close (p > 0.1)

Although a large effect size was observed (OR: 11.0), this association did not reach statistical significance ( P = .109).

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