Local infrared stimulation modulates spontaneous cortical slow wave dynamics in anesthetized rats.

Sci Rep · 2026 · PMC12929577 · PMID 41644725

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0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significancep = 0.080so close (0.05 < p ≤ 0.1)

S 1 A), although this difference did not reach statistical significance ( p = 0.080, paired t-test).

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a decreasing trendno p-value reported

The CV of up-state durations exhibited a decreasing trend during stimulation, with 7 out of 8 animals showing lower CVs compared to baseline (BL: 0.374 ± 0.073; ON: 0.348 ± 0.081; Supplementary Fig.

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a weak trendno p-value reported

Together, these results suggest a weak trend toward reduced variability in state durations, indicating that infrared stimulation may render cortical slow-wave activity slightly more rhythmic, as also illustrated in Fig. 1 C.

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showed a trendno p-value reported

LFP amplitude and spectral changes varied across cortical regions: PtA exhibited increased slow wave (0.5–2 Hz) and high delta (2–4 Hz) band activity, while S1Tr showed a trend toward reduction.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.